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KMID : 0374919940150040661
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Inje Medical Journal
1994 Volume.15 No. 4 p.661 ~ p.666
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The Effect of Clonidine and Morphine nfused by Epidural Catheter for Postoperative Pain Control of Cesarean Sectioned Patients
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박장수
김정원/문순홍/신동엽/홍기혁
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Abstract
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Clonidine has been known to have analgesic effect, when it was especially given epidurally and intrathecally. So clonidine can be an alternative to morphine for patients with chronicpain severe side effects from morphine. We gave bolus of 600
microgram
of clonidine and continuous infuaion of morphine 4 milligram and clonidine 960 microgram for 48 hours to 20 cesarean sectioned fecmales postoperatively via epidural catheter.
Compated with epidural morphine alone, clonidine bolus and continuous morphine mixed with clonidine has onset of analgesic effcet and far less side effects such as pruritus, nausea and vomiting.
But clonidine can cause severe hypotension and bradycardia, so careful titreation of dosage and post infusion close monitoring are required.
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KEYWORD
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